{"id":197724,"date":"2020-12-07T21:30:12","date_gmt":"2020-12-07T20:30:12","guid":{"rendered":"https:\/\/www.realites.com.tn\/?p=197724"},"modified":"2020-12-07T21:30:12","modified_gmt":"2020-12-07T20:30:12","slug":"covid-19-le-molnupiravir-pourrait-stopper-la-transmission-du-virus-en-24h","status":"publish","type":"post","link":"https:\/\/realites.com.tn\/fr\/covid-19-le-molnupiravir-pourrait-stopper-la-transmission-du-virus-en-24h\/","title":{"rendered":"Covid-19 : le Molnupiravir pourrait stopper la transmission du virus en 24h"},"content":{"rendered":"
\n
En une journ\u00e9e, ce m\u00e9dicament serait capable de bloquer la transmission du virus, selon une \u00e9tude am\u00e9ricaine.<\/div>\n
Dans le monde entier, les scientifiques travaillent \u00e0 l\u2019\u00e9laboration d\u2019un vaccin contre le Covid-19. Mais, c\u00f4t\u00e9 traitement, les choses avancent \u00e9galement. Des chercheurs de l’Institut des sciences biom\u00e9dicales de la Georgia State University ont d\u00e9couvert l\u2019antiviral, MK-4482 \/ EIDD-2801 ou Molnupiravir, pouvant supprimer compl\u00e8tement la transmission du virus dans les 24 heures.<\/div>\n
\u201cIl s’agit de la premi\u00e8re d\u00e9monstration d’un m\u00e9dicament disponible par voie orale pour bloquer rapidement la transmission du SRAS-CoV-2. Le MK-4482 \/ EIDD-2801 pourrait changer la donne\u201d, a d\u00e9clar\u00e9 le Dr Richard Plemper, professeur \u00e9m\u00e9rite \u00e0 l’Universit\u00e9 de G\u00e9orgie (Etats-Unis). L\u2019\u00e9tude assure que ce m\u00e9dicament aurait un triple potentiel : inhiber la progression des patients vers une maladie grave, raccourcir la phase infectieuse pour soulager le bilan \u00e9motionnel et socio-\u00e9conomique de l’isolement prolong\u00e9 du patient et faire taire rapidement les flamb\u00e9es locales. Les conclusions de cette \u00e9tude ont \u00e9t\u00e9 publi\u00e9es dans la revue Nature Microbiology.<\/div>\n
\u201cNous avons not\u00e9 tr\u00e8s t\u00f4t que le MK-4482 \/ EIDD-2801 a une activit\u00e9 \u00e0 large spectre contre les virus \u00e0 ARN respiratoire et que le traitement des animaux infect\u00e9s par voie orale avec le m\u00e9dicament r\u00e9duit la quantit\u00e9 de particules virales excr\u00e9t\u00e9es de plusieurs ordres de grandeur, r\u00e9duisant consid\u00e9rablement la transmission. Ces propri\u00e9t\u00e9s ont fait du MK-4482 \/ EIDD \/ 2801 un candidat puissant pour le contr\u00f4le pharmacologique du COVID-19\u201d, note le Dr Plemper.<\/div>\n
Pour tester l\u2019efficacit\u00e9 de ce m\u00e9dicament, les chercheurs ont utilis\u00e9 un mod\u00e8le de furet. \u201cNous pensons que les furets sont un mod\u00e8le de transmission pertinent car ils propagent facilement le SRAS-CoV-2, mais ne d\u00e9veloppent g\u00e9n\u00e9ralement pas de maladie grave, qui ressemble \u00e9troitement \u00e0 la propagation du SRAS-CoV-2 chez les jeunes adultes\u201d, rapporte le Dr Robert Cox, stagiaire postdoctoral et co-auteur principal de l’\u00e9tude. Les chercheurs ont inject\u00e9 le m\u00e9dicament \u00e0 des furets infect\u00e9s par le virus. \u201cLorsque nous avons plac\u00e9 ces animaux infect\u00e9s puis trait\u00e9s avec des furets non-trait\u00e9s dans la m\u00eame cage, aucun des contacts n’a \u00e9t\u00e9 infect\u00e9\u201d, a d\u00e9clar\u00e9 Josef Wolf, \u00e9tudiant au doctorat au laboratoire Plemper et co-auteur principal de l’\u00e9tude. Ces donn\u00e9es doivent maintenant \u00eatre confirm\u00e9es chez les hommes. Ainsi, ce m\u00e9dicament permettrait aux patients de devenir non-infectieux 24 heures apr\u00e8s le d\u00e9but du traitement.<\/div>\n
(Yahoo Actualit\u00e9s)<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

En une journ\u00e9e, ce m\u00e9dicament serait capable de bloquer la transmission du virus, selon une \u00e9tude am\u00e9ricaine. Dans le monde entier, les scientifiques travaillent \u00e0 l\u2019\u00e9laboration d\u2019un vaccin contre le…<\/p>\n","protected":false},"author":60,"featured_media":197725,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_lmt_disableupdate":"","_lmt_disable":"","_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[7],"tags":[],"class_list":["post-197724","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-monde"],"yoast_head":"\nCovid-19 : le Molnupiravir pourrait stopper la transmission du virus en 24h - R\u00e9alit\u00e9s Magazine<\/title>\n<meta name=\"description\" content=\"En une journ\u00e9e, ce m\u00e9dicament serait capable de bloquer la transmission du virus, selon une \u00e9tude am\u00e9ricaine. 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